Wegovy® (Semaglutide) Safety Information

Before Using Wegovy®

Tell your healthcare provider about your full medical history, including if you have:

Kidney, liver, or pancreas problems

Severe gastrointestinal disease

A history of diabetic retinopathy

Depression, suicidal thoughts, or behavior changes

Discuss all prescription and non-prescription medications, vitamins, and herbal supplements you take, especially:

Insulin or insulin secretagogues (e.g., sulfonylureas)

Thyroid hormone medication

Medications with a narrow therapeutic range (e.g., warfarin)

Pregnancy, Breastfeeding & Contraception

Do not use if you are pregnant, planning to become pregnant, or breastfeeding.

Stop Wegovy® at least 2 months before trying to conceive.

Use effective contraception while on treatment.

Wegovy® may cause fetal harm.

Alcohol

Avoid alcohol while taking Wegovy®.

Serious Warnings: Call Your Doctor Immediately If You Experience:

Thyroid C-cell tumor symptoms (see Black Box Warning above)

Pancreatitis: severe abdominal or back pain that does not go away, with or without vomiting

Gallbladder disease: pain in the upper right stomach, fever, yellowing skin or eyes, nausea or vomiting

Kidney problems or failure: reduced urination, swelling, fatigue, especially if dehydrated from nausea, vomiting, or diarrhea

Hepatitis or elevated liver enzymes: yellowing skin or eyes, dark urine

Diabetic retinopathy changes: sudden vision changes

Serious allergic reaction: swelling of face, lips, tongue, or throat; difficulty breathing or swallowing; rash, itching, fainting, dizziness, or rapid heartbeat

Severe gastrointestinal issues

Hypoglycemia (especially if also taking insulin or sulfonylureas): dizziness, confusion, sweating, rapid heartbeat, shakiness, headache

Increased heart rate

Worsening depression or suicidal thoughts

If any of these occur, stop Wegovy® and seek immediate medical attention.

Common Side Effects

Some people experience no side effects. The most common include:

Nausea, vomiting, diarrhea, constipation, abdominal pain, bloating, belching, flatulence

Headache, dizziness, fatigue

Indigestion, upset stomach, acid reflux

Nasopharyngitis (common cold)

Back pain

Altered taste

Decreased appetite

Injection site reactions

Gastroenteritis

Increased lipase or amylase

Most side effects improve as your body adjusts. Contact your provider if symptoms persist.

Drug Interactions

Wegovy® may delay stomach emptying, which can affect absorption of oral medications.

Dose adjustments may be required for insulin, sulfonylureas, thyroid hormone, and medications with a narrow therapeutic index.

Monitor closely if on warfarin or other blood thinners.

Other Safety Notes

Stay hydrated to reduce risk of dehydration-related kidney issues.

Never share your Wegovy® pen with anyone, even if the needle is changed.

Emergency Information

In case of a medical emergency, call 911 or go to the nearest emergency room.

To report side effects, contact the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.