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What is TB-500 and how does it work?

From the Belle care team · Updated

TB-500 is a lab-made peptide used to support recovery from injury and training.

It is a lab-made piece of thymosin beta-4, a protein that helps your cells move to areas that need repair. Most of the research so far is in animals or small studies, so human data is limited and we will not promise more than the evidence shows. Results are not guaranteed and they vary from person to person.

When will I notice something?

The human research on TB-500 is early, so there is no established timeline for results, and we would rather tell you that than guess. Your provider will talk through what you can realistically expect.

How is it taken?

A small injection under the skin once a day, for 8 weeks on and then 2 weeks off. Your dose and what comes with your plan are in "How do I store, handle, and inject TB-500?"

How is it different from BPC-157?

BPC-157 is another recovery peptide Belle offers. The two come from different proteins and have been studied for different things. Some people ask about using them together. Whether one, or both, makes sense for you is your provider's call.

Who should not take TB-500

TB-500 is not right for you if you are pregnant, breastfeeding, or trying to conceive, if you have active cancer or are in cancer treatment, or if you have a family history of colon cancer. It is also not prescribed with active liver disease or severe kidney disease, with an allergy to peptide medicines, or under the age of 18.

One thing for competitive athletes

TB-500 is on banned lists for many sports, so it is not for athletes who are tested for banned substances.

Is TB-500 FDA approved?

No. TB-500 is an investigational peptide, and it isn't FDA approved for any use. What Belle prescribes is a compounded medication, and compounded medications are not reviewed by the FDA for safety, effectiveness or quality. Its long-term safety in people isn't established. It is available by prescription only, after a licensed provider reviews your health history.

Is it the same as the TB-500 sold online?

No. Most TB-500 sold online is labeled for research use, not for people, with no prescription and no verified purity or dose. Belle's TB-500 is prescribed by a US-licensed provider and filled by a US-licensed pharmacy.

Can I take it with my other Belle treatments?

That depends on what you take, so it is your provider's call. They review TB-500 alongside everything else you are on, including a GLP-1 or another Belle treatment, before prescribing it.

Is it available in my state?

TB-500 is not available in every state yet. The current list is in "Peptide plans, shipments, and billing: how it works".

What about side effects?

See "TB-500 side effects and what's normal".

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