What is microdosing a GLP-1?

Microdosing means taking a lower-than-standard dose of a GLP-1 — usually because your goal is something other than active weight loss.

It is an informal term, not a medical definition. Your plan includes a personalized dosing plan from a licensed provider.

What counts as a microdose

The standard starting dose of tirzepatide is 2.5 mg. A microdose is any dose below what is normally used to drive weight loss.

Two ways people use it

• Start low and build slowly. Begin at a very low dose, see how you respond, and titrate up gradually toward a standard dose.
• Stay low over time. Remain at a low dose because active weight loss is not the goal.

What to expect for weight loss

Many do not see sustained weight loss at these low doses.

If active weight loss is your main goal, a standard dosing plan is usually the better fit. Weight loss is not promised, and results vary.

Who it can fit

• Patients new to GLP-1s who want to start at a lower dose
• Patients who prefer to stay at a lower dose rather than push for maximum weight loss
• Patients at their goal weight who have already stepped down to around 5 mg of tirzepatide

Only a licensed provider decides whether microdosing is a fit for you, and what your dose should be.

Already reached your goal weight?

Keeping weight off after you reach your goal usually starts by stepping your dose down gradually (sometimes called a maintenance plan). Once you have stepped down to around 5 mg of tirzepatide, the Microdose plan can be a way to stay at a low dose. It is not a jump from a high dose: step down first. Switching is a new order, so your current plan is cancelled and you complete a short questionnaire; message us and we will send you the link. See "Reaching your goal weight: how maintenance works at Belle" for the full picture.

Questions about whether it is right for you

Whether microdosing suits your situation, and what dose you would be on, are decisions for your provider. Message us and we will get your question to the right person.