Can I get compounded GLP-1 without B vitamins?

Short answer: Yes.

If you have an allergy or sensitivity to B vitamins, your compounded GLP-1 is made with L-carnitine or glycine instead of a B vitamin. Neither one is a B vitamin.

Most tirzepatide patients now receive the L-carnitine version anyway, so you may already be on a formulation without B vitamins. Check your vial label, or message us and we will confirm.

What's in it

Most compounded GLP-1 medications include an added ingredient beyond the active drug, often a B vitamin such as pyridoxine (B6), cyanocobalamin (B12), or niacinamide (B3).

For patients with a B vitamin allergy or sensitivity, Belle's pharmacy partners use one of these instead:

• L-carnitine: an amino acid derivative. Not a B vitamin.
• Glycine: a naturally occurring amino acid added as a buffering agent. Not a B vitamin.

Belle no longer offers a version with no added ingredient at all. Always check the label that ships with your order for a complete ingredient list.

Who qualifies?

A formulation without B vitamins is available to patients who indicate a B vitamin allergy or sensitivity on their Belle intake questionnaire. Your clinician reviews this as part of your treatment plan.

Important: This is a clinical pathway for patients with a genuine B vitamin allergy or sensitivity, not a preference-based option.

How do I get it?

If you're a new patient: Indicate your B vitamin allergy or sensitivity when you complete your intake questionnaire. Your clinician will factor it into your treatment plan from your first prescription.

If you're already a Belle patient and did not indicate a B vitamin allergy during your original intake: message your care team through the patient portal, and we'll update your record and coordinate with your clinician.

Whether you get L-carnitine or glycine depends on which pharmacy partner fills your order. Your label lists every ingredient.

Will it work the same as standard compounded GLP-1?

Yes. The active medication is the same, tirzepatide or semaglutide, at the same prescribed dose. The added ingredient doesn't change your dose or how your medication works.