A Belle member asked
Struggling
28 replies · 🤢 managing side effects · Oct 2026
Hi…..Im really having a tough time. Im in my 7th week of tirz. 7th shot was last night side effects have been minimal until last week. for 2 or 3 days I had the belching, some diarrhea a tons of stomach gurgling. I do my shots on Thurs. eves. and stomach didn't calm till Monday. Felt great Tues Wed and all day yesterday. This morning I was nauseous but felt better after eating something. Was fine most of day but due to circumstances, I couldn't eat till around 4pm and it was a quick single serve frozen pizza. Not ideal I know but I was in. hurry, starving and knew I had to eat. Water intake good. Then about an hour after eating ans ever since, I'm belching all the time, stomach gurgling is back and have diarrhea again . Oh,and Im very tired. I took activated charcoal which I take sparingly and not with any other meds as it can eliminate effects. I am wondering how long I’m going to deal with the side effects. I almost want to give up.
- Belle member
Have you gone up on your dose recently ?
- Belle member
I take a digestive enzyme , brand is Thermedix, and I get it on Amazon. It has been helping me with nausea and belching. I take one morning and at night right after I eat.
- Belle member
You need to reach out to the care team. They can help!
- Belle member
I would look at what youve been eating that may be causing it. But ive been on Zepbound and now compounded tirz since 11/2025 and each week can be different quite honestly. But once youve been on the same dose for a while it evens out and less side effects is what Ive found. Everyone is different though!
- Belle member
@member No....I forgot to mention that.
- Belle member
@member thanks! Ill check it out!
- Belle member
@member Lange thanks. I had an appt. scheduled and then I felt better ams canceled . But I definitely will tomorrow.
- Belle member
@member let us know how it goes!
- Belle member
@member maybe splitting the dose might help. The care team will be a big help
- Belle member
@member thanks.....I will contact them.
- Belle member
Is the care team available on Saturday?
- Belle member
@member sometimes. They say they are available Monday through Friday but I have posted questions and got answers during the weekend. I would still ask for help right away. At the very least, you will be first in line on Monday!
- Belle member
Im sorry you're having a hard time. When I first started, I had nausea. I learned that I need to make sure I get my protein, fiber, and electrolytes in the day before and after. Sometimes, because Im not hungry, I will have protein drinks, yogurt, eggs, sweet potatoes, and foods that are a bit easier to digest. Don't give up!! Between speaking to your care team and tips from the community, I'm sure you can get it under control.
- Belle member
Sorry your experiencing that it not fun. I had some issues like diarrhea and the sulfur burps along with headaches usually 2-3 days after I moved up to high. Don’t give up reach out to the medical team and they can give you some guidance. I had kept a food log and found that some foods triggered me so I made sure to take a digestive enzyme if I had something I knew would trigger it so I didn’t have to avoid it Just hang in there and reach out to them don’t give up
- Belle member
Sorry to hear you’re having a hard time. I had the sulfur burps and diarrhea a couple time it lasted about 2 days. A friend gave me so brioschi you add it to water and it bubbles that did help. They make hard candy too. Toast also helped, but you should message belle they are very good about responding right back and they were very helpful to me.
- Belle member
@member thank you
- Belle member
A lot of frozen foods contain ingredients that cause this.. including frozen pizza that often has a lot of vegetable oil and weird things that are hard to digest. To me it seems kind of classic to get those effects after eating it. And then being really tired after having diarrhea. It can be very draining to get sick like that. I also get acid reflux from it, depending on what brand it is. There’s only like one type I can tolerate. It sounds like you were doing ok before the pizza besides normal side effects the day after your shot.
- Belle member
@member most definitely! It was not a great day situationally and then having not eaten wasn't good until having that pizza, blah. I definitely so desire more lean foods being on this med. so thatbis a plus!
- Belle member
@member I think you will be okay and not have these problems if your food is less processed and is more healthy. Don’t give up! It’s not the tirz so you can definitely do this 💕
- Belle member
Hang in there it will get better once you figure out what yiu can and can't eat.
- Belle member
Hi Constance, I’d make sure you are not sick for another reason. If you have had not side effects and they started after your 7th shot (and on your 3rd day), maybe its side effects?…but maybe it is a stomach bug. If symptoms don’t improve, get worse and you can’t keep hydrated, I’d reach out to your PCP before making any other changes to your plan. Not every single symptom has to be GLP1 related. Good luck to you and hope you feel better
- Belle member
@member I really hope you get a solution and don’t give up. I been there and now I am I’m in maintenance so it does get better once you find the causes
- Belle member
@member thanks.....I exoerinced the same after last weeks shot as well. Last week I actually thought part of what Inwas experiencing was a stomach bug. I even sent a message to my primary care provider and she suspected that too. She knows Im on glp and I described symptoms. I feel awful. Im going to talk with someone at Bell o. Monday.....maybe try split dosing the 2.5 MG.
- Belle member
@member thank you! That is encouraging!
- Belle member
@member a lot of what I found out about GLP1 is like trail and error even in maintenance. Fingers crossed for you
- Belle member
@member thank you
- Belle member
May be food balancing related. I had all kinds of odd symptoms throughout and every time I ate in a balanced Whole Foods way the symptoms would diminish
- Belle member
Try taking your shot in the morning. Moving around during the day will help with the belching. Lying down lets gas accumulate. Split dosing gives me zero side effects. Try it. Of course, consult first.
Shared by Belle members about their own experience. Not medical advice: ask your care team before changing anything.