If you’re gaining weight despite doing all the “right” things, it might not be about willpower—it might be your hormones. Midlife weight gain, PCOS, perimenopause, and insulin resistance can all disrupt how your body stores fat and manages hunger.
GLP-1 medications like semaglutide and tirzepatide are helping more people take back control, even when hormones are working against them. Here’s how.
Hormones influence everything from appetite and metabolism to fat storage and insulin sensitivity. When key hormones like estrogen, progesterone, cortisol, and insulin become imbalanced, your body can start to hold on to weight—especially around the midsection.
You may experience:
GLP-1 medications mimic a hormone your body naturally makes to regulate appetite, blood sugar, and digestion. These medications work in several ways that are especially useful for hormonally driven weight gain:
By addressing both the metabolic and behavioral components of weight gain, GLP-1s create a foundation for lasting change.
GLP-1 therapy is being used more frequently for people dealing with:
These conditions often come with increased inflammation, hormonal fluctuations, and disrupted appetite signals—areas where GLP-1s can help restore balance.
GLP-1s do more than help you lose fat. Patients often report better energy, more stable moods, fewer crashes between meals, and more confidence around food choices. When hormones feel out of control, that stability can be life-changing.
You don’t need a specific diagnosis like diabetes or obesity to be considered. At Belle, our providers look at your whole health picture—including symptoms like fatigue, hunger, hormonal changes, or unexplained weight gain—to help determine the best path forward.
No insurance approvals. No judgment. Just real care on your terms.
